osteopontin Antibodies

Target Information

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. Belongs to the osteopontin family. Bone. Found in plasma. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

2AR; 44 kDa bone phosphoprotein; AA960535; AI790405; Apl-1; BNSP; Bone sialoprotein 1; bone sialoprotein I; Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; Early T-lymphocyte activation 1 protein; Eta; ETA-; ETA-1; Eta-1; MGC110940; Minopontin; Nephropontin; Op; OPN; Opn; Opnl; ost; Osteopontin; osteopontin-like protein; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; OSTP; OTTMUSP00000029095; OTTMUSP00000029097; OTTMUSP00000029098; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; secreted phosphoprotein-1 (osteopontin, bone sialoprotein); SPP-1; SPP1; Spp1; SPP1/CALPHA1 fusion; Urinary stone protein; Uropontin