TRPS1 Antibodies
Target Information
Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
GC79; LGCR; MGC134928; transcriptional repressor GATA binding 1; Tricho-rhino-phalangeal syndrome type I protein; trichorhinophalangeal syndrome I; TRPS1; Zinc finger protein GC79; Zinc finger transcription factor Trps1TRPS1 Antibody Products
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