What is the difference between the Phospho-Tau (Thr217) Matched Antibody Pair #70933 and the Phospho-Tau (Thr217) Matched Antibody Pair II #51525?

The main difference between the Phospho-Tau (Thr217) Matched Antibody Pair #70933 and Matched Antibody Pair II #51525 is the capture antibody used in each pair.

Both pairs use the same phospho-specific detection antibody, but they differ in where the capture antibody binds along the Tau protein:

• #70933 uses a capture antibody that recognizes a more N-terminal region of Tau
• #51525 uses a capture antibody that recognizes a more C-terminal region of Tau

This difference in epitope location can affect what you are measuring in your assay. For example, many blood-based biomarker assays commonly use an N-terminal capture antibody (as in #70933). Importantly, neither pair is inherently better, they simply provide different approaches to measuring phospho-Tau (Thr217). Offering both options allows you to choose the format that best aligns with your sample type and research goals.

Last updated: April 23, 2026