What DNA library prep kit do you recommend using for CUT&RUN?

We recommend using our SimpleChIP^® ChIP-seq DNA Library Prep Kit for Illumina^® #56795 for making DNA libraries with CUT&RUN or ChIP DNA. This kit should be paired with our SimpleChIP^® ChIP-seq Multiplex Oligos for Illumina^® (Dual Index Primers) #47538 or SimplechIP^® ChIP-seq Multiplex Oligos for Illumina^® (Single Index Primers) #29580.

Last updated: October 6, 2025