Does your Insulin (C27C9) Rabbit mAb #3014 detect proinsulin?

Our Insulin (C27C9) Rabbit mAb #3014 was produced with an antigenic peptide corresponding to residues within the insulin B chain of the human insulin protein (UniProt ID #P01308; https://www.uniprot.org/uniprot/P01308). Therefore, it is expected to recognize both proinsulin and mature insulin. While this antibody is not approved for use in western blotting, it should be able to detect the proinsulin protein if the gel is run carefully enough.

We also offer an Insulin (L6B10) Mouse mAb #8138, which is approved for use in western blotting on rat samples. This antibody detects both proinsulin and insulin as well.

Last updated: October 6, 2025