Name: ZBTB32 (F5O1L) Rabbit Monoclonal Antibody
Price: 161.00 USD
Availability: InStock

Filter:

WB
F

Product Specifications

REACTIVITY	M
SENSITIVITY	Endogenous
MW (kDa)	50
Source/Isotype	Rabbit IgG

Application Key:

WB-Western Blotting
F-Flow Cytometry

Species Cross-Reactivity Key:

M-Mouse

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000
Flow Cytometry (Fixed/Permeabilized)	1:100 - 1:400

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

实验步骤

Specificity / Sensitivity

ZBTB32 (F5O1L) Rabbit Monoclonal Antibody recognizes endogenous levels of total ZBTB32 protein.

Species Reactivity:

Mouse

Source / Purification

Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of mouse ZBTB32 protein.

Background

Zinc finger and BTB domain-containing 32 (ZBTB32), also known as testis zinc finger protein (TZFP) and repressor of GATA3 (ROG), is a transcription factor that belongs to the BTB/POZ-ZF protein family and was first identified in immune cell development and tumorigenesis (1,2). These transcription factor family members contain an N-terminal BTB/POZ domain, which mediates dimerization, and a C-terminal domain with a variable number of zinc fingers that bind DNA (3). ZBTB32 plays a role in T cell homeostasis and inhibits the development of Th2 cells by repressing GATA3 (4,5), and is required for the regulation of CD8⁺ T cells in response to viral infection (6). ZBTB32 is highly expressed by a subset of human and mouse memory B cells but not by naïve B cells (7,8), and is essential for the proliferative burst of natural killer (NK) cells in vivo (9).

Alternate Names

4930524C15Rik; FAXF; FAZF; GATA repressor; OTTMUSP00000026619; PLZP; Repressor of GATA; Rog; Testis zinc finger protein; Tzf; Tzfp; ZBT32; Zbtb32; zinc finger and BTB domain containing 32; Zinc finger and BTB domain-containing protein 32

Database Links

UniProt ID: Q9JKD9

Entrez-Gene Id: 58206

限制使用

除非 CST 的合法授书代表以书面形式书行明确同意，否书以下条款适用于 CST、其关书方或分书商提供的书品。任何书充本条款或与本条款不同的客书条款和条件，除非书 CST 的合法授书代表以书面形式书独接受，否书均被拒书，并且无效。

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For Research Use Only. Not for Use in Diagnostic Procedures.

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ZBTB32 (F5O1L) Rabbit Monoclonal Antibody #94103