Name: Ym1/Chi3l3 (F7T7N) Rabbit Monoclonal Antibody
Price: 161.00 USD
Availability: InStock

Filter:

WB

Product Specifications

REACTIVITY	M
SENSITIVITY	Endogenous
MW (kDa)	44
Source/Isotype	Rabbit IgG

Application Key:

WB-Western Blotting

Species Cross-Reactivity Key:

M-Mouse

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

实验步骤

Specificity / Sensitivity

Ym1/Chi3l3 (F7T7N) Rabbit Monoclonal Antibody recognizes endogenous levels of total Ym1/Chi3l3 protein. This antibody does not cross-react with Ym2/Chi3l4 or AMCase/Chia proteins. This antibody detects a 28 kDa protein of unknown identity in some cell lines and tissues.

Species Reactivity:

Mouse

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp275 of mouse Ym1/Chi3l3 protein.

Background

Chitinase-like protein 3 (CHI3L3), also called Ym1, is a rodent specific chitinase-like protein (CLP) (1,7). Chitinases are a class of chitin-degrading enzymes produced in the host, which play a protective role in innate immunity against the chitin-containing pathogens, including parasites, fungi, and arthropods (1,2,7). In healthy tissues, Ym1 is expressed in the spleen, bone marrow, and lung (7). Ym1 expression can be induced by various inflammatory stimuli, such as allergic airway inflammation, parasitic infection, or autoimmune disease (7). Ym1 is primarily produced by alternatively activated (M2) macrophages and is often used as a marker for these cells (3-7).

Alternate Names

AI505981; Beta-N-acetylhexosaminidase Ym1; Chi3; Chi3l3; CHIL3; chitinase 3-like 3; chitinase-3-like protein 3; chitinase-like 3; Chitinase-like protein 3; ECF-L; Eosinophil chemotactic cytokine; eosinophil chemotactic factor-L; O35744; Secreted protein Ym1; Ym1

Database Links

UniProt ID: O35744

Entrez-Gene Id: 12655

限制使用

除非 CST 的合法授书代表以书面形式书行明确同意，否书以下条款适用于 CST、其关书方或分书商提供的书品。任何书充本条款或与本条款不同的客书条款和条件，除非书 CST 的合法授书代表以书面形式书独接受，否书均被拒书，并且无效。

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For Research Use Only. Not for Use in Diagnostic Procedures.

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Ym1/Chi3l3 (F7T7N) Rabbit Monoclonal Antibody #89984