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  3. REDD1 (F7T9B) Rabbit Monoclonal Antibody
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Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

REDD1 (F7T9B) Rabbit Monoclonal Antibody #20629

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  • WB
  • IP

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 28
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:50

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    实验步骤

    Specificity / Sensitivity

    REDD1 (F7T9B) Rabbit Monoclonal Antibody recognizes endogenous levels of total REDD1 protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the full-length of human REDD1 protein.

    Background

    Regulated in development and DNA damage responses 1 (REDD1), also known as DNA damage-inducible transcript 4 protein (DDIT4), is a 25 kDa stress response protein whose expression is induced by hypoxia, cell stress, apoptosis, and DNA damage. REDD1 is a transcriptional target of p53 and p63 following DNA damage, linking p63 to the regulation of reactive oxygen species (1). REDD1 functions as a negative regulator of mTOR in response to hypoxia in a tuberin-dependent manner (2). Depending on cell context, REDD1 can be protective or detrimental to cells under oxidative or ischemic stress (3).

    Alternate Names

    DDIT4; Dig2; DNA damage inducible transcript 4; DNA damage-inducible transcript 4 protein; DNA-damage-inducible transcript 4; FLJ20500; HIF-1 responsive protein RTP801; HIF-1 responsive RTP801 (RTP801); Protein regulated in development and DNA damage response 1; REDD-1; REDD1; RP11-442H21.1; RTP801

    Database Links

    UniProt ID: Q9NX09


    Entrez-Gene Id: 54541


    限制使用

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    For Research Use Only. Not for Use in Diagnostic Procedures.
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