Name: PRDX6 (D9J9H) Rabbit Monoclonal Antibody
Price: 351.00 USD
Availability: InStock

Filter:

WB

Product Specifications

REACTIVITY	H
SENSITIVITY	Endogenous
MW (kDa)	25
Source/Isotype	Rabbit IgG

Application Key:

WB-Western Blotting

Species Cross-Reactivity Key:

H-Human

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

实验步骤

Specificity / Sensitivity

PRDX6 (D9J9H) Rabbit Monoclonal Antibody recognizes endogenous levels of total PRDX6 protein.

Species Reactivity:

Human

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human PRDX6 protein.

Background

Peroxiredoxin 6 (PRDX6) belongs to an antioxidant enzyme family of non-seleno peroxidases. PRDX6 is a unique member of the PRDX family, exhibiting both glutathione peroxidase and phospholipase A2 activities (1,2). PRDX6 regulates phospholipid turnover in addition to protecting cells against oxidative injury. PRDX6 is expressed in all major organs, with a particularly high level in lung, where it regulates lung surfactant phospholipid synthesis and turnover (3-5). Research studies have shown that PRDX6 is aberrantly expressed in various cancers, and can promote cancer cell metastasis and invasion (6,7). Elevated expression of PRDX6 and related PRDX family members has also been shown to contribute to drug resistance in cancer cells (8,9). PRDX6 is also expressed in neutrophils, where it has been shown to activate NADPH oxidase (NOX2) (10-12).

Alternate Names

1-Cys; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2; Antioxidant protein 2; AOP2; epididymis secretory sperm binding protein Li 128m; Glutathione-dependent peroxiredoxin; HEL-S-128m; KIAA0106; Liver 2D page spot 40; MGC46173; Non-selenium glutathione peroxidase; NSGPx; p29; peroxiredoxin 6; Peroxiredoxin-6; PRDX6; PRX; Red blood cells page spot 12

Database Links

UniProt ID: P30041

Entrez-Gene Id: 9588

限制使用

除非 CST 的合法授书代表以书面形式书行明确同意，否书以下条款适用于 CST、其关书方或分书商提供的书品。任何书充本条款或与本条款不同的客书条款和条件，除非书 CST 的合法授书代表以书面形式书独接受，否书均被拒书，并且无效。

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For Research Use Only. Not for Use in Diagnostic Procedures.

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PRDX6 (D9J9H) Rabbit Monoclonal Antibody #64329