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  3. PP5 Antibody

PP5 Antibody #2289

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  • WB

    Product Specifications

    REACTIVITY H M R Mk
    SENSITIVITY Endogenous
    MW (kDa) 58
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 
    • Mk-Monkey 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    实验步骤

    Specificity / Sensitivity

    PP5 Antibody detects endogenous levels of total PP5 protein.

    Species Reactivity:

    Human, Mouse, Rat, Monkey

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the amino-terminal sequence of human PP5. Antibodies are purified by protein A and peptide affinity chromatography.

    Background

    Protein phosphatase 5 (PP5) is a member of the serine/threonine phosphatase family that also includes PP1, PP2A and PP2B. PP5 uniquely contains an amino-terminal regulatory domain with three tetratricopeptide repeat (TPR) motifs and a carboxy-terminal catalytic domain (1-3). Through the TPR domain, PP5 interacts with a number of proteins and has been reported to be involved in diverse signal transduction pathways, including glucocorticoid receptor signaling, p53-mediated growth arrest, oxidative stress-mediated apoptosis and the response to ionizing radiation-induced DNA damage (4-8).

    Alternate Names

    FLJ36922; PP-T; PP5; PPP5; PPP5C; PPT; protein phosphatase 5 catalytic subunit; protein phosphatase 5, catalytic subunit; Protein phosphatase T; Serine/Threonine phosphatase; Serine/threonine-protein phosphatase 5

    Database Links

    UniProt ID: P53041


    Entrez-Gene Id: 5536


    限制使用

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    For Research Use Only. Not for Use in Diagnostic Procedures.
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