Name: Metavinculin (F3R2D) Rabbit Monoclonal Antibody
Price: 178.00 USD
Availability: InStock

Filter:

WB
IP
IHC

Product Specifications

REACTIVITY	H
SENSITIVITY	Endogenous
MW (kDa)	145
Source/Isotype	Rabbit IgG

Application Key:

WB-Western Blotting
IP-Immunoprecipitation
IHC-Immunohistochemistry

Species Cross-Reactivity Key:

H-Human

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000
Simple Western™	1:10 - 1:50
Immunoprecipitation	1:100
Immunohistochemistry (Paraffin)	1:200 - 1:800

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

实验步骤

Specificity / Sensitivity

Metavinculin (F3R2D) Rabbit Monoclonal Antibody recognizes endogenous levels of total metavinculin protein. Based on the sequence of the peptide antigen, this antibody is not expected to detect vinculin.

Species Reactivity:

Human

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro943 of human metavinculin protein.

Background

Vinculin is a cytoskeletal protein localized to cell-matrix and cell-cell adhesion complexes with roles in cell adhesion, migration, and signal transduction (1). Metavinculin is a vinculin isoform resulting from alternative splicing containing a 68-residue insert (2). Metavinculin is expressed in cardiac and smooth muscle (3), and mutations in the metavinculin insert are associated with various cardiomyopathies (4). Metavinculin protein functions in the cytoskeleton with roles in actin bundling, focal adhesion formation, and cell adhesion and migration (5-7).

Alternate Names

CMD1W; CMH15; epididymis luminal protein 114; epididymis secretory sperm binding protein; HEL114; meta-vinculin; Metavinculin; MV; MVCL; VCL; VINC; Vinculin

Database Links

UniProt ID: P18206

Entrez-Gene Id: 7414

限制使用

除非 CST 的合法授书代表以书面形式书行明确同意，否书以下条款适用于 CST、其关书方或分书商提供的书品。任何书充本条款或与本条款不同的客书条款和条件，除非书 CST 的合法授书代表以书面形式书独接受，否书均被拒书，并且无效。

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For Research Use Only. Not for Use in Diagnostic Procedures.

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Metavinculin (F3R2D) Rabbit Monoclonal Antibody #64558