Name: G0S2 (F7A7O) Rabbit Monoclonal Antibody
Price: 161.00 USD
Availability: InStock

Filter:

WB
IP

Product Specifications

REACTIVITY	H
SENSITIVITY	Endogenous
MW (kDa)	11
Source/Isotype	Rabbit IgG

Application Key:

WB-Western Blotting
IP-Immunoprecipitation

Species Cross-Reactivity Key:

H-Human

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000
Immunoprecipitation	1:50

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

实验步骤

Specificity / Sensitivity

G0S2 (F7A7O) Rabbit Monoclonal Antibody recognizes endogenous levels of total G0S2 protein.

Species Reactivity:

Human

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human G0S2 protein.

Background

G0/G1 switch gene 2 (G0S2) is a small protein involved in several biological processes. G0S2 is involved in cell cycle regulation; G0S2 mRNA was initially found to be upregulated in lymphocytes during the G0 to G1 cell cycle transition, whereas low G0S2 protein levels are associated with higher turnover of CD8⁺ T cells and several cancer types (1-3). G0S2 directly interacts with adipose triglyceride lipase (ATGL) to inhibit lipolysis (4). G0S2 is also upregulated in various inflammatory diseases, including rheumatoid arthritis, Crohn's disease, systemic lupus erythematosus, and psoriasis (5-8). Mature, activated neutrophils highly express G0S2, and it may represent part of an anti-tumor neutrophil signature (9,10).

Alternate Names

G0/G1 switch 2; G0/G1 switch protein 2; G0/G1 switch regulatory protein 2; G0/G1switch 2; G0S2; OTTHUMP00000034644; P27469; Putative lymphocyte G0/G1 switch gene; RP1-28O10.2

Database Links

UniProt ID: P27469

Entrez-Gene Id: 50486

限制使用

除非 CST 的合法授书代表以书面形式书行明确同意，否书以下条款适用于 CST、其关书方或分书商提供的书品。任何书充本条款或与本条款不同的客书条款和条件，除非书 CST 的合法授书代表以书面形式书独接受，否书均被拒书，并且无效。

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For Research Use Only. Not for Use in Diagnostic Procedures.

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G0S2 (F7A7O) Rabbit Monoclonal Antibody #10789