Name: ADA2B (F6G5T) Rabbit Monoclonal Antibody
Price: 376.00 USD
Availability: InStock

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WB

Product Specifications

REACTIVITY	H M R Mk
SENSITIVITY	Endogenous
MW (kDa)	55
Source/Isotype	Rabbit IgG

Application Key:

WB-Western Blotting

Species Cross-Reactivity Key:

H-Human
M-Mouse
R-Rat
Mk-Monkey

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

实验步骤

Specificity / Sensitivity

ADA2B (F6G5T) Rabbit Monoclonal Antibody recognizes endogenous levels of total ADA2B protein. This antibody does not cross-react with ADA2A protein.

Species Reactivity:

Human, Mouse, Rat, Monkey

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp172 of human ADA2B protein.

Background

ADA2A and ADA2B are human homologs of the yeast SAGA complex member Ada2. While highly related, ADA2A and B appear functionally distinct. ADA2A is incorporated into PCAF-containing complexes, while ADA2B is recruited to SAGA complexes with GCN5 and Brg1 (1-3). ADA2 proteins form a trimer with GCN5L and ADA3, and enhance GCN5L acetyltransferase activity (4,5). The C-terminal domain of ADA2A and ADA2B determines incorporation into their various complexes, resulting in specific targeting toward histone H3 or H4 (6).

Alternate Names

ADA2-beta; ADA2-like protein beta; ADA2(beta); ADA2B; MGC21874; TAD2B; TADA2B; Transcriptional adapter 2-beta; transcriptional adaptor 2 (ADA2 homolog, yeast)-beta; transcriptional adaptor 2B

Database Links

UniProt ID: Q86TJ2

Entrez-Gene Id: 93624

限制使用

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For Research Use Only. Not for Use in Diagnostic Procedures.

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ADA2B (F6G5T) Rabbit Monoclonal Antibody #10691