Cell Signaling Technology Logo
1% for the planet logo

HTScan® PDK1 Kinase Assay Kit #7577

Inquiry Info. # 7577

Please see our recommended alternatives.

    Product Information

    Product Description

    The kit provides a means of performing kinase activity assays with recombinant human PDK1 kinase. It includes active PDK1 kinase (supplied as a GST fusion protein), a biotinylated peptide substrate and a phospho-serine/threonine antibody for detection of the phosphorylated form of the substrate peptide.
    Molecular Formula Biotin-peptide: 2,205 Daltons. PDK1 Kinase: 67 kDa.

    Background

    Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways (1,2) including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK (3). Through its effects on these kinases, PDK1 is involved in the regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis.

    Alternate Names

    3-phosphoinositide dependent protein kinase-1; enzyme; hPDK1; kinase; kinase PDK1; mPDK1; PDPK1; PkB kinase; Protein kinase B kinase

    For Research Use Only. Not for Use in Diagnostic Procedures.
    Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.
    All other trademarks are the property of their respective owners. Visit our Trademark Information page.