WHSC1L1 Antibodies

Target Information

Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

DKFZp667H044; FLJ20353; Histone-lysine N-methyltransferase NSD3; KMT3F; KMT3G; MGC126766; MGC142029; NSD3; nuclear receptor binding SET domain protein 3; Nuclear SET domain-containing protein 3; pp14328; Protein whistle; WHISTLE; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; WHSC1-like protein 1; WHSC1L1; Wolf-Hirschhorn syndrome candidate 1-like 1; Wolf-Hirschhorn syndrome candidate 1-like 1 protein; Wolf-Hirschhorn syndrome candidate 1-like protein 1