PU.1 Antibodies

Target Information

Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. Belongs to the ETS family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

31 kDa transforming protein; 31 kDa-transforming protein; Dis; Dis-1; Dis1; hematopoietic transcription factor PU.1; OF; OTTMUSP00000015228; PU.; PU.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfp; Sfpi-1; SFPI1; Sfpi1; SPI-1; Spi-1; SPI-1 proto-oncogene; SPI-A; SPI1; Spi1; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; Tcfpu; Tcfpu1; Tfpu.; Tfpu.1; Transcription factor PU.1