MYH10 Antibodies

Target Information

Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

Cellular myosin heavy chain, type B; cellular myosin heavy chain, type B type B; MGC134913; MGC134914; MYH10; Myosin heavy chain 10; Myosin heavy chain, non-muscle IIb; myosin heavy chain, nonmuscle type B; Myosin-10; myosin, heavy chain 10, non-muscle; myosin, heavy polypeptide 10, non-muscle; near to the ATP binding region; NMMHC II-b; NMMHC-B; NMMHC-IIB; NMMHCB; Non-muscle myosin heavy chain B; Non-muscle myosin heavy chain IIb; nonmuscle myosin heavy chain IIB; nonmuscle myosin heavy chain-B; nonmuscle myosin II heavy chain-B