MAIR-I Antibodies

Target Information

Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6. Belongs to the CD300 family. Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

B230315M08Rik; CD300 antigen-like family member A; CD300A; Cd300a; CD300A antigen; CD300a antigen; CD300A molecule; CD300a molecule; Clm; CLM-8; CLM8; Clm8; CMRF-35-H9; CMRF-35H; CMRF35-H; CMRF35-H9; CMRF35-like molecule 8; CMRF35H; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35H9; IGSF12; Immunoglobulin superfamily member 12; Inhibitory receptor protein 60; IRC1; IRC1/IRC2; IRC2; IRp60; leukocyte membrane antigen; Leukocyte mono-Ig-like receptor 1; Lmir1; MAIR-1; MAIR-I; MAIR-Ia; Mast cell-derived paired immunoglobulin-like receptor 1; Mcpir1; MMAC; MMAC8; Myeloid-associated immunoglobulin-like receptor 1; NK inhibitory receptor; OTTMUSP00000003633; Pigr4; polymeric immunoglobulin receptor 4