PGAM1 Antibody

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Product Name

12098 PGAM1 (D3J9T) Rabbit mAb

Filter:

WB

Inquiry Info. # 7534

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Supporting Data

REACTIVITY	H M R Mk
SENSITIVITY	Endogenous
MW (kDa)	28
SOURCE	Rabbit

Application Key:

WB-Western Blotting

Species Cross-Reactivity Key:

H-Human
M-Mouse
R-Rat
Mk-Monkey

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

PGAM1 Antibody recognizes endogenous levels of total PGAM1 protein.

Species Reactivity:

Human, Mouse, Rat, Monkey

Source / Purification

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro128 of human PGAM1 protein. Antibodies are purified by protein A and peptide affinity chromatography.

Background

Phosphoglycerate mutase (PGAM1) catalyzes the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis (1-5). Research studies have shown increased PGAM1 expression in cancer (1-4) and mental disease (5). Specifically, PGAM1 was shown to be phosphorylated at His11 by phosphoenolpyruvate (PEP) in PKM2-expressing cells, suggesting a possible regulatory role for PGAM1 in actively proliferating cells via an alternative glycolytic pathway (1).

Alternate Names

BPG-dependent PGAM 1; mutase; PGAM-B; PGAM1; PGAMA; Phosphoglycerate; Phosphoglycerate mutase; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 brain; phosphoglycerate mutase A nonmuscle form; Phosphoglycerate mutase isozyme B

Database Links

UniProt ID: P18669

Entrez-Gene Id: 5223

限制使用

除非 CST 的合法授书代表以书面形式书行明确同意，否书以下条款适用于 CST、其关书方或分书商提供的书品。任何书充本条款或与本条款不同的客书条款和条件，除非书 CST 的合法授书代表以书面形式书独接受，否书均被拒书，并且无效。

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For Research Use Only. Not for Use in Diagnostic Procedures.

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PGAM1 Antibody #7534