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Commit: 7ed46ecc04b401f23a28df741b5078df405d23e4
XML generation date: 2026-05-20 10:23:43.318
Product last modified at: 2026-05-21T08:00:11.440Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
  1. Products /
  2. Primary Antibodies /
  3. ALDH1L1 (E7I2Q) Rabbit Monoclonal Antibody (BSA and Azide Free)
Recombinant Flag
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

ALDH1L1 (E7I2Q) Rabbit Monoclonal Antibody (BSA and Azide Free) #57508

Filter:
  • WB
  • IF

    Product Specifications

    REACTIVITY H M R
    SENSITIVITY Endogenous
    MW (kDa) 98
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IF-Immunofluorescence 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 

    Product Information

    Product Usage Information

    This product is the carrier free version of product #85828. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol.

    This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us. Optimal dilutions/concentrations should be determined by the end user.

    BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.

    Formulation

    Supplied in 1X PBS (10 mM Na2HPO4, 3 mM KCl, 2 mM KH2PO4, and 140 mM NaCl (pH 7.8)). BSA and Azide Free.

    For standard formulation of this product see product #85828

    Storage

    Store at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.

    Specificity / Sensitivity

    ALDH1L1 (E7I2Q) Rabbit Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total ALDH1L1 protein. This antibody detects a non-specific band of unknown origin in rodent tissue extracts at 47 kDa.

    Species Reactivity:

    Human, Mouse, Rat

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val431 of human ALDH1L1 protein.

    Background

    Aldehyde dehydrogenase 1 family member L1 (ALDH1L1), also known as 10-formyltetrahydrofolate dehydrogenase (FDH), is a member of the aldehyde dehydrogenase super family. It is a key enzyme in folate metabolism, playing an important role in regulation of cellular metabolism including proliferation (1,2). Downregulation of ALDH1L1 has been seen in tumors, leading to decreased suppression of cancer cell proliferation (2,3).

    ALDH1L1 has also been shown to be a useful astrocyte marker throughout the gray and white matter of the brain, labeling both the cell body and processes of astrocytes. ALDH1L1 does not label oligodendrocytes or neurons (4). It has been shown that expression of ALDH1L1 in astrocytes is stably expressed through normal tissue and during astrogliosis (5).

    Alternate Names

    10-formyltetrahydrofolate dehydrogenase; 10-fTHF; 10-FTHFDH; AL1L1; aldehyde dehydrogenase 1 family member L1; aldehyde dehydrogenase 1 family, member L1; aldehyde dehydrogenase 1L1; Aldehyde dehydrogenase family 1 member L1; ALDH1L1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; FDH; formyltetrahydrofolate dehydrogenase; FTHFD; MER57B-ALDH1L1

    Database Links

    UniProt ID: O75891


    Entrez-Gene Id: 10840


    限制使用

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    For Research Use Only. Not for Use in Diagnostic Procedures.
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