Cat. # | Size | Price | Inventory |
---|---|---|---|
8655T | 1 Kit (8 x 20 microliters) |
Product Includes | Quantity | Applications | Reactivity | MW(kDa) | Isotype |
---|---|---|---|---|---|
CD44 (156-3C11) Mouse mAb 3570 | 20 µl |
|
H | 80 | Mouse IgG2a |
Cyclin D1 (92G2) Rabbit mAb 2978 | 20 µl |
|
H M R | 36 | Rabbit IgG |
c-Jun (60A8) Rabbit mAb 9165 | 20 µl |
|
H M R Mk | 43, 48 | Rabbit IgG |
LEF1 (C12A5) Rabbit mAb 2230 | 20 µl |
|
H M R | 25-58 | Rabbit IgG |
Met (D1C2) XP® Rabbit mAb 8198 | 20 µl |
|
H | 140, 170 | Rabbit IgG |
MMP-7 (D4H5) XP® Rabbit mAb 3801 | 20 µl |
|
M R | 28, 20-22 | Rabbit |
c-Myc (D84C12) Rabbit mAb 5605 | 20 µl |
|
H M R | 57-65 | Rabbit IgG |
TCF1/TCF7 (C63D9) Rabbit mAb 2203 | 20 µl |
|
H M | 48, 50 | Rabbit IgG |
Anti-mouse IgG, HRP-linked Antibody 7076 | 100 µl |
|
Horse | ||
Anti-rabbit IgG, HRP-linked Antibody 7074 | 100 µl |
|
Goat |
Product Information
Rabbit monoclonal antibodies are produced by immunizing animals with a GST-c-Jun protein corresponding to the amino-terminal sequence of human c-Jun protein or synthetic peptides corresponding to residues near the amino terminus of c-Myc protein, residues surrounding Pro82 of human LEF1 protein, residues surrounding Ile264 of mouse MMP-7 protein, residues surrounding Pro95 of human TCF1/TCF7 protein, residues near the carboxy terminus of human Met protein, or residues near the carboxy-terminus of human cyclin D1 protein.
The mouse monoclonal antibody is produced by immunizing BALB/c mice with stimulated human leukocytes for CD44.
The Wnt family includes several secreted glycoproteins that play important roles in animal development. β-catenin is a key downstream effector of the Wnt signaling pathway that research studies have shown is implicated in early embryonic development and tumorigenesis in vertebrates (1-3). Following binding of Wnt family proteins to the Frizzled receptor, β-catenin translocates to the nucleus where it interacts with LEF1 and TCF1 to activate canonical targets (4). Accepted canonical targets include CD44, cyclin D1, c-Jun, c-Myc, Met, and MMP-7 (5-11).
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