Name: SCD5 (F6Z4R) Rabbit Monoclonal Antibody
Price: 161.00 USD
Availability: InStock

Filter:

WB
IP

Product Specifications

REACTIVITY	H
SENSITIVITY	Endogenous
MW (kDa)	29
Source/Isotype	Rabbit IgG

Application Key:

WB-Western Blotting
IP-Immunoprecipitation

Species Cross-Reactivity Key:

H-Human

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000
Immunoprecipitation	1:100

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

实验步骤

Specificity / Sensitivity

SCD5 (F6Z4R) Rabbit Monoclonal Antibody recognizes endogenous levels of total SCD5 protein.

Species Reactivity:

Human

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human SCD5 protein.

Background

Human stearoyl-CoA desaturase 5 (SCD5), also known as acyl-CoA-desaturase 4 (ACOD4), is an isoform of stearoyl-CoA desaturase (SCD) in the endoplasmic reticulum membrane that converts saturated fatty acids into monounsaturated fatty acids. There are human SCD5 orthologs in primates but not in rodents. Human SCD5 exhibits a similar Δ9-desaturase activity to SCD1 and has been shown to desaturate stearoyl-CoA (C18:0) to its corresponding monounsaturated fatty acid (1-3). Studies suggest that SCD5 is a regulator of neuronal cell growth and differentiation (3). Furthermore, SCD5 exhibits a substrate preference for C18:0 and is essential for glioblastoma stem cell (GSC) self-renewal, survival, and tumor initiation (4).

Alternate Names

ACOD4; Acyl-CoA-desaturase 4; FADS4; FLJ21032; HSCD5; SCD2; SCD4; SCD5; Stearoyl-CoA 9-desaturase; Stearoyl-CoA desaturase 2; stearoyl-CoA desaturase 4; Stearoyl-CoA desaturase 5

Database Links

UniProt ID: Q86SK9

Entrez-Gene Id: 79966

限制使用

除非 CST 的合法授书代表以书面形式书行明确同意，否书以下条款适用于 CST、其关书方或分书商提供的书品。任何书充本条款或与本条款不同的客书条款和条件，除非书 CST 的合法授书代表以书面形式书独接受，否书均被拒书，并且无效。

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For Research Use Only. Not for Use in Diagnostic Procedures.

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SCD5 (F6Z4R) Rabbit Monoclonal Antibody #37434