Revision 1

#3828

Store at -20C

Forskolin

10 mg

CST Logo
Orders:

877-616-CELL (2355)

[email protected]

Support:

877-678-TECH (8324)

3 Trask Lane | Danvers | Massachusetts | 01923 | USA

For Research Use Only. Not for Use in Diagnostic Procedures.

Background

Forskolin, a naturally occurring diterpene from the Indian plant, Coleus forskohlii, activates adenylate cyclase, and thus increases the intracellular cAMP concentration (1). The second messenger cAMP activates cAMP-dependent protein kinase (PKA or cAPK) and controls many cellular mechanisms such as gene transcription, ion transport and protein phosphorylation (2).

Molecular Formula

C22H34O7

Molecular Weight

410.5 g/mol

Purity

>99%

CAS

66575-29-9

Solubility

Soluble in DMSO at 10mg/ml and EtOH at 4mg/ml.

Storage

Store lyophilized or in solution at -20ºC, desiccated. Protect from light. In lyophilized form, the chemical is stable for 24 months. Once in solution, use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Directions for Use

For 30 mM stock, reconstitute 10 mg in 812 μl DMSO.

Trademarks and Patents

Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.

All other trademarks are the property of their respective owners. Visit cellsignal.com/trademarks for more information.

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Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

#3828

Forskolin

Cell Signaling Technology Logo
Western blot analysis of extracts from SH-SY5Y cells, forskolin-treated (30uM for 15 min.) or untreated, using Phospho-Creb (Ser133) Rabbit mAb #9198 (upper) or CREB Rabbit mAb #9197 (middle).
undefined Image 1: Forskolin
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.