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传染病与病毒学

传染病与病毒学

感染性疾病由病毒、真菌、细菌或寄生虫等致病生物的侵袭引起。随着病毒等病原体进入宿主细胞并繁殖,关键的细胞过程会受到影响。Indeed, the life cycle of viral pathogens co-opts and deregulates many aspects of host cell biology such as vesicle trafficking, anti-viral innate immune response, protein translation, and cell-cycle regulation. 宿主生物体以多种方式对病毒感染作出反应,包括利用免疫系统的适应性和先天性分支。宿主免疫应答的性质在病毒性疾病发病机制中起着重要作用。免疫反应较弱会增加感染的严重程度,而免疫过度反应可能具有有害作用。此外,一些病毒病原体已开发出逃避宿主免疫应答的策略,从而允许更有效的传播。登革热、普通感冒、流感、寨卡病毒、HIV/AIDS 等疾病的发病机制可通过免疫反应逃逸、免疫系统缺陷或炎症传播。Cell Signaling Technology (CST) offers a unique portfolio of antibodies capable of specifically detecting different post-translational modifications on key signaling proteins, which are often altered by viral pathogens during the course of infection. 此外,我们提供各种经高度验证的总蛋白抗体,以询问通常被诸如 SARS-CoV-2 等病原体破坏的宿主细胞生物学过程。

病毒感染

A viral infection engages multiple branches of the host immune system, which can affect the viral replication cycle, the infected cells, or both. CST provides validated antibodies and recombinant proteins that can be used in your research focused on understanding the host immune response to viral infection and viral-host protein-protein interactions.

宿主对病毒的反应

Understanding the host response to viral infection is important for unraveling disease mechanisms and developing effective therapeutics. The host response during a viral infection is modulated by a number of cellular signaling pathways. Our expert scientists can work with you to find the best approach and products to investigate and combat emerging viral diseases.

SARS-CoV-2

SARS-CoV-2 is a novel coronavirus that causes COVID-19 and is under intense investigation to understand its evolution and high infectivity rate. To assist you in important research to combat the pandemic, CST offers antibodies, recombinant proteins, kits, and reagents that target SARS-CoV-2 including ACE2 and spike proteins.

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