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产品结果

癌症

癌症

癌症是一种复杂且异质性的疾病,由遗传或表观遗传变化破坏正常细胞功能引起。为了更好地了解基础机制,Hanahan 和 Weinberg 11 创建了一份癌症特征和两种使能特征列表,其中包括: self-sufficiency in growth signals, insensitivity to anti-growth signals, evading apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion and metastasis, reprogramming energy metabolism and evading immune response, and the two enabling traits: 基因组不稳定性和突变、肿瘤促炎等。Cell Signaling Technology (CST) 拥有丰富的专业知识,其产品目录广泛、极其可靠、灵敏且经过验证,能够支持从开发新型疗法到发现癌症发病机制的新见解的各种动态的癌症研究需求。

癌症标志

The 11 hallmarks of cancer as described by Hanahan and Weinberg provide an organizational structure for understanding cancer cell genotypes and assisting in development of novel therapeutics. CST offers the tools to interrogate these hallmarks through a comprehensive catalog of reliable and validated antibodies that target the following mechanisms: sustaining proliferative signaling, evading growth suppressors, avoiding immune destruction, enabling replicative immortality, tumor promoting inflammation, activating invasion and metastasis, inducing angiogenesis, genome instability and mutation, and resisting cell death.

癌症研究分析和对照

Cell-based assays in cancer research are important tools for probing signaling pathways involved in tumorigenesis and metastasis. CST offers a variety of assays and kits that aid in the characterization of important cancer mechanisms and cellular pathways including: ALK and ROS1, caspase-3 activity, epigenetic biomarkers, and regulators and histone modifications for across a range of cancer types.

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# 产品名称 应用 反应性
H, M, R, Hm, Mk, C, Dm, B, Dg, Pg, GP
H, M, R, Hm, Mk, Dm, Z, B
H, M, R, Hm, Mk, Dm, B, Dg
H, M, R, Mk, B, Pg
H, M, R, Mk
H, M, R, Mk, Dm
H, M, R, Mk
H, M, R, Hm, Mk
H, M, R
H, M, R, Mk
H, M, R, Mk
H, M, R, Mk
H, M, R, Mk
H, M, R
H, M, R, Mk
H, M, R, Mk
H, M, R, Mk
H, M, R, Mk
H, M, R, Mk, Sc
H, M, R, Mk
H, M, R, Mk
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H, M, R, Mk
H, M, R, Mk, Mi, Sc
H, M, R, Hm, Mk
H, M, R, Mk
H, M, R, Mk
H, M, R, Mk
H, M, R
H, M, R, Mk
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